Conference Programme

The full conference programme is available below. You can also download the programme as a PDF file

          

Day 1 - Wednesday 23rd July, 2014

Conference Opening

08:30 09:30 Registration

09:30 09:35 Professor Julia Buckingham - Vice Chancellor: Welcome to the UK and Brunel University
09:35 09:50 Svetlana Ignatova - Chair of CCC2014: 14 years of Progress
Session 1 - Method Development
09:50 10:10 FO1 - Guido Pauli Chicago, IL, USA Guess Again: Development of a Countercurrent-based Threshold Assay for Ginkgotoxin Isomers
10:10 10:30 FO2 - Shihua Wu Hangzhou, China Targeted Strategy for Natural products Isolation by Counter-current Chromatography Using a Novel 9×9 Solvent Map
10:30 10:40 SO1 - J.Brent Friesen River Forest, IL, USA Qualitative and Quantitative Evaluation of Solvent Systems for Countercurrent Separation.
10:40 10:50 SO2 - Thomas Pogiatzis London, UK Predicting the solubility of pharmaceutical components with the SAFT-γ Mie group contribution approach
10:50 11:00 SO3 - Abigail Engelberth West Lafayette, IN , USA Selection of a Non-Aqueous Solvent System for the Separation of Hemicellulose-Based Sugars
11:00 11:30 Tea & Coffee, Posters & Exhibition





Session 2 New Solvents
11:30 11:40 SO4 - Alain Berthod Lyon, France Limonene in "green" Arizona Liquid Systems used in CCC
11:40 11:50 SO5 - Aneta Spórna-Kucab Warszawska, Poland New solvent systems used in gradient-CCC for separation of polar betalains from Beta vulgaris L.
11:50 12:00 SO6 - Jizhong Yan Hangzhou, China Chiral ligand exchange high speed counter-current chromatography: mechanism, application and comparison with conventional liquid chromatography in enantioseparation of ten aromatic α-hydroxyl acids
12:00 12:10 SO7 - Mirjana Minceva Erlangen, Germany Potential application of non-conventional aqueous two phase systems in counter-current and centrifugal partition chromatography
12:10 12:20 SO8 - Leslie Brown Belfast, Northern Ireland Novel applications of Ionic Liquid–Liquid Chromatography / Extraction (ILLC™ / ILLE™) in CCC and CPC
12:20 12:40 Flash Poster Presentations for Sessions 1&2
12:40 14:00 Lunch, Posters & Exhibition





Session 3 Process Development
14:00 14:45 K1 - Jean-Hugues Renault Riems, France Keynote on pH Zone Refining and Ion Exchange (TBC)
14:45 15:05 FO3 - Duo-Long Di Lanzhou, China Preparative Separation and Purification of Active Chemical Compounds from Nature Products by HSCCC Coupled with Other Techniques
15:05 15:25 FO4 - Jane Hubert
Metabolite profiling of natural extracts: A de-replication strategy based on centrifugal partition extraction combined to 13C NMR chemical shift pattern recognition
15:25 15:55 Tea & Coffee, Posters & Exhibition





Session 4 Scale-up and Continuous Processing
15:55 16:15 FO5 - Philip Wood Slough, UK Differences in Stationary Phase Retention between normal phase and reverse phase in J-type centrifuges caused by the influence of coriolis acceleration
16:15 16:35 FO6 - Fernanda Costa  Rio de Janeiro, Brazil Intra- and inter-apparatus scale-up CCC using the isolation of masticadienonic and 3β-masticadienolic acids from Schinus terebinthifolius as example
16:35 16:45 SO9 - Johannes Goll Erlangen, Germany Model-based Design of Centrifugal Partition Chromatographic Process for Continuous Fractionation of Multicomponent Mixtures 
16:45 17:00 Flash Poster Presentations for Sessions 3&4
17:00 18:00 Posters & Exhibition, Cash Bar





Day 2 - Thursday 24th July, 2014

Industry Day Opening

08:30 09:00 Registration for Industry Day
09:00 09:15 Sir Richard Sykes - Chancellor: Introduction to Industry Day
Session 5 Industry Day 

09:15 09:45 K2 - Ian A. Sutherland Uxbridge, UK Review of Industrial Scale-up of CCC/CPC 2000-2014
09:45 10:05 FO7 - GaryW. Yanik Palm Beach Gardens, FL , USA Automating Method Development and Prep Purification in Counter Current Chromatography (CCC)
10:05 10:25 FO8 - David Thornton King of Prussia, PA , USA Development and Scale-up of Countercurrent Chromatography Process 
10:25 10:55 Tea & Coffee, Posters & Exhibition





Session 6 Industrial Case Studies 1
10:55 11:15 FO9 - Adrian Weisz College Park, MD , USA Preparative Separation of Novel Subsidiary Colors of D&C Red No. 33 (Acid Red 33) Using Spiral Countercurrent Chromatography
11:15 11:35 FO10 - Paul Hellier Gaillac, France pH Zone Refining in Centrifugal Partition Extraction- A Step Change in Productivity for Liquid-Liquid Chromatography Processes
11:35 11:55 FO11 - Carl DeAmicis Indianapolis, IN, USA Productivity and Performance Comparison of Countercurrent Chromatography and Reverse Phase HPLC at Pilot Scale – A Case Study of Spinosyns Purification
11:55 12:15 FO12 - Lijuan Chen Chengdu, China Honokiol Case Study
12:15 14:00 Lunch, Posters & Exhibition





Session 7 Industrial Case Studies 2
14:00 14:20 FO13 - Nathalie Douillet Stevenage, UK Breakthrough in oligonucleotide purification?
14:20 14:40 FO14 - Peter Hewitson  Uxbridge, UK A new dynamic fractionation method and column design for size separation of bio-polymer particles
14:40 14:50 SO10 - Jonas Krause Dortmund, Germany Enzymatic Reactions in Aqueous/Organic Two Phase Systems using Centrifugal Partition Chromatography as a Reactor
14:50 15:20 Flash Poster Presentations for Industry Day
15:20 15:50 Tea & Coffee, Posters & Exhibition





Session 8 ATPS

15:50 16:10 FO15 - Jon Huddleston Uxbridge, UK Purification of Antibody-based Material by Counter-Current Liquid-Liquid Extraction
16:10 16:30 FO16 - Christopher Ladd Effio Karlsruhe, Germany Evaluation of Centrifugal Partition Chromatography for the purification of virus-like particles
16:30 17:00 Panel Discussion

17:00 18:00 Posters & Exhibition, Cash Bar
19:00
Conference Dinner






Day 3 - Friday 25th July, 2014

Session 9 Novel Approaches & Emerging Technology
09:00 09:45 K3 - Petr Fedotov Moscow, Russia Field-Flow Fractionation of Nano- and Microparticles in Rotating Coiled Columns 
09:45 10:05 FO17 - Hiroyuki Shiono Aichi, Japan Continuous separation of mouse dendritic cells by the flow-through density gradient centrifugation
10:05 10:15 SO11 - Masami Shibukawa Saitama, Japan Multi-Step pH-Peak-Focusing Countercurrent Chromatography – the Useful Method for Separation and Enrichment of Metal Ions
10:15 10:30 Flash Poster Presentations (x3)
10:30 11:00 Tea & Coffee, Posters & Exhibition





Session 10 Applications 1

11:00 11:45 K4 - Gerold Jerz Braunschweig, Germany The Lab-Scale CCC Toolbox for Recovery of Bioactive Natural Products Linked to Mass-spectrometry Profiling Methods
11:45 11:55 SO12 - Xueli Cao Beijing, China Application of High-performance CCC as a Preconcentration and Cleanup Method for the Determination of Contaminants in Food Samples
11:55 12:20 Flash Poster Presentations
12:20 14:00 Lunch, Posters & Exhibition





Session 11 Instrumentation, Process Modelling & Theory
14:00 14:20 FO18 - Christof Schwienheer Dortmund, Germany Evaluation of CPC separation efficiency for different types of chamber geometries on the basis of flow pattern and separation experiments 
14:20 14:40 FO19 - Alexis Kotland Saint-Nazaire, France Modeling pH Zone Refining CPC separations: a dynamic approach
14:40 14:50 SO13 - Kazufusa Shinomiya Chiba, Japan Fabrication of Coil Satellite Centrifuge and Its Partition Efficiency on Counter-Current Chromatographic Separation of 4-Methylumbelliferyl Sugar Derivatives with Organic-Aqueous Two-phase Solvent Systems
14:50 15:00 SO14 - Eiichi Kitazume Iwate, Japan Large-Scale Hydrodynamic CCC based on an Archimedean Screw for Purification of Effluent
15:00 15:10 SO15 - Gerhard Schembecker Dortmund, Germany Countercurrent Centrifugal Extraction
15:10 15:25 Flash Poster Presentations
15:25 15:50 Tea & Coffee, Posters & Exhibition





Session 12 Applications 2

15:50 16:10 FO20 - Michael Englert-Vetter-140429 Stuttgart, Germany Application of pH-zone-refining countercurrent chromatography for the preparative separation of fatty acids from vegetable oils 
16:10 16:20 SO16 - Nektariosd Aligiannis Athens, Greece Use of CPC as a choice method for the bio-guided study of plant extracts
16:20 16:30 SO17 - Gilda Leito Rio de Janeiro, Brazil Synthesis of New Naphthoxazole Derivatives of Lapachol and their Separation by Countercurrent chromatography
16:30 17:00 Flash Poster Presentations





17:00 17:30 Closing Remarks, Award of Prizes & Announcements for Next Meeting
19:00
Pub Crawl for Stoics






Day 4 - Saturday 26th July, 2014



Social Programme