Countercurrent Chromatography 2014

Separation technology and scale-up of separation processes are one of the major challenges facing industry today. This conference series highlights the progress being made in new processes where the sample is simply kept in a liquid stream.

Counter-current chromatography (CCC) and Centrifugal Partition Chromatography (CPC) are unique liquid-liquid extraction/chromatography processes with a support free liquid stationary phase. As both phases are liquid either phase can be the mobile phase opening up a range of different operating modes, including continuous processing. There is no adsorption to solid supports, particulates are tolerated and the high volume proportion of stationary phase means that there is high loading capacity and high resolution separation with a low number of theoretical plates.

When the 1st International Conference on CCC was held in London in September 2000, the technology was only just evolving as a laboratory process.

Now, 14 years on, the technology is commercially robust, competitive at an industrial scale and finding application in many laboratory and industrial scale separations including recovery of target chemicals from waste streams.

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